GEO DataSets

(Submitter supplied) Albeit majority of eukaryotic genome can be pervasively transcribed to a diverse population of lncRNAs and various subtypes of lncRNA have been discovered. However, the genome-wide study of miRNA-derived lncRNAs is still lacking. Here, we report that over 800 miRNA gene-originated lncRNAs (molncRNAs) generated from miRNA loci. One of them, molnc-301b from miR-301b and miR-130b, functions as an "RNA decoy" to facilitate dissociation of the chromatin remodeling protein SMARCA5 from chromatin and thereby sequester transcription and mRNA translation. more...

Organism:

Homo sapiens; synthetic construct

Type:

Expression profiling by high throughput sequencing; Other

Platforms:

GPL20795 GPL24676 GPL26697

40 Samples

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