GSM5699231[Accession] - GEO DataSets

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Items: 3

Select item 2001893261.

SENP2 suppresses browning of white adipose tissues by de-conjugating SUMO from C/EBPβ

(Submitter supplied) The adipose tissue is a key site regulating energy metabolism. One of the contributing factors behind this is browning of white adipose tissue (WAT), however, knowledge of the intracellular determinants of browning process remains incomplete. By generating adipocyte-specific Senp2 knockout (Senp2-aKO) mice, here we showed that SENP2 negatively regulates browning by de-conjugating SUMO from C/EBPβ. Senp2-aKO mice were resistant to diet-induced obesity and insulin resistance due to increased energy expenditure and heat production. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL13912
8 Samples

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Accession:: GSE189326

ID:: 200189326

Select item 1000139122.

Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version)

(Submitter supplied) Design ID: 028005 Build version: mm9:NCBI37:Jul2007 Arrays of this design have barcodes that begin with 16028005 or 2528005. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...