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Items: 3

1.

SENP2 suppresses browning of white adipose tissues by de-conjugating SUMO from C/EBPβ

(Submitter supplied) The adipose tissue is a key site regulating energy metabolism. One of the contributing factors behind this is browning of white adipose tissue (WAT), however, knowledge of the intracellular determinants of browning process remains incomplete. By generating adipocyte-specific Senp2 knockout (Senp2-aKO) mice, here we showed that SENP2 negatively regulates browning by de-conjugating SUMO from C/EBPβ. Senp2-aKO mice were resistant to diet-induced obesity and insulin resistance due to increased energy expenditure and heat production. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
24 Samples
Download data: TXT
Series
Accession:
GSE189387
ID:
200189387
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

e1-1: eWAT_Cont_siNS_1

Organism:
Mus musculus
Source name:
SVF-derived adipocyte
Platform:
GPL21273
Series:
GSE189387
Download data: TXT
Sample
Accession:
GSM5700439
ID:
305700439
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db=gds|term=GSM5700439[Accession]|query=1|qty=2|blobid=MCID_6677b3638c5d4760e2e33422|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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