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Items: 3

1.

The bone marrow niche regulates redox and energy balance in leukemia stem cells

(Submitter supplied) The Cxcr4-Cxcl12 axis has been postulated as a critical pathway dictating leukemia stem cell (LSCs) chemoresistance in AML due to its role in controlling cellular egress from the marrow. Nevertheless, the cellular source of Cxcl12 in the AML microenvironment and the mechanism by which Cxcl12 exert its protective role in AML in vivo remain unresolved. We have evaluated the functional role of Cxcl12 secreted by early mesenchymal stromal cells (MSCs) and osteolineage committed cells in acute myeloid leukemia (AML) maintenance in vivo. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
18 Samples
Download data: TXT
Series
Accession:
GSE189928
ID:
200189928

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Mus musculus)

Organism:
Mus musculus
10366 Series
297584 Samples
Download data
Platform
Accession:
GPL19057
ID:
100019057

3.

LSCs, cxcl12_WT2_1

Organism:
Mus musculus
Source name:
Bone marrow
Platform:
GPL19057
Series:
GSE189928
Download data
Sample
Accession:
GSM5710057
ID:
305710057

SRA Run Selector

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db=gds|term=GSM5710057[Accession]|query=1|qty=2|blobid=MCID_67574e8b79cb8359a295d85e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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