GSM5815132[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2001936241.

Med1 controls effector CD8+ T cell differentiation and survival through mediating the transcriptional regulation of C/EBPβ on T-bet

(Submitter supplied) Effector CD8+ T cells are crucial in adaptive immunity for effective protection against infectious pathogens. The regulatory mechanisms underlying CD8+ effector T cell development are incompletely understood. Here, we defined a critical role of mediator complex subunit 1 (Med1) in controlling effector CD8+ T cell differentiation and survival during acute infections. Mice with Med1 deletion in CD8+ T cells exhibited a significantly impaired effector cell expansion with large reduction of KLRG1+ terminally differentiated and Ly6c+ effector cell populations. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13112
6 Samples

Download data: TXT

Series

Accession:: GSE193624

ID:: 200193624

PubMed Similar studies

Select item 1000131122.

Illumina HiSeq 2000 (Mus musculus)

Organism:: Mus musculus

8328 Series
188391 Samples

Platform

Accession:: GPL13112

ID:: 100013112

Select item 3058151323.

Organism:: Mus musculus

Source name:: Spleen_CD8 T cells

Platform:: GPL13112
Series:: GSE193624

Sample

Accession:: GSM5815132

ID:: 305815132

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GSM5815132[Accession] (3)
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