GSM5856155[Accession] - GEO DataSets

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Items: 4

Select item 2001959051.

Characterization of dynamic p300 enhancers in murine cardiomyocyte development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL21103 GPL24247 GPL19057
48 Samples

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Series

Accession:: GSE195905

ID:: 200195905

PubMed Full text in PMC Similar studies

Select item 2001959022.

Characterization of dynamic p300 enhancers in murine cardiomyocyte development [RNA-seq]

(Submitter supplied) We report the application of bioChIP-seq, bulk RNA-seq, Hi-C, and Massively parallel reporter assays (MPRAs) to characterize the p300-bound regulatory regions in murine cardiomyocytes (CMs). By obtaining ChIP-seq data of coactivator p300 from seven developmental stages of mouse CMs, we defined the dynamic p300 enhancers from embryonic CMs to adult CMs. We then validated the activity of dynamic p300 enhancers with AAV9-based MPRAs, we found dynamic p300 enhancers show dynamic activity from postnatal day 0 (P0) CMs to 4-week-old CMs. more...