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Items: 4

1.

Context-dependent perturbations in chromatin folding and the transcriptome by cohesin and related factors [ChIP-seq]

(Submitter supplied) Cohesin plays vital roles in chromatin folding and gene expression regulation, cooperating with such factors as cohesin loaders, unloaders, and the insulation factor CTCF. Although models of regulation have been proposed (e.g., loop extrusion), how cohesin and related factors collectively or individually regulate the hierarchical chromatin structure and gene expression remains unclear. We have depleted cohesin and related factors and then conducted a comprehensive evaluation of the resulting 3D genome, transcriptome and epigenome data. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL30173 GPL16791
61 Samples
Download data: BED, BW
Series
Accession:
GSE196727
ID:
200196727
2.

Context-dependent perturbations in chromatin folding and the transcriptome by cohesin and related factors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL16791 GPL20795 GPL30173
126 Samples
Download data: BED, BW, HIC, TXT
Series
Accession:
GSE196450
ID:
200196450
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

ChIP-seq CTCF siCTCF

Organism:
Homo sapiens
Source name:
RPE cells
Platform:
GPL16791
Series:
GSE196450 GSE196727
Download data: BED, BW
Sample
Accession:
GSM5899611
ID:
305899611
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Supplemental Content

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