GSM5942336[Accession] - GEO DataSets

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Items: 4

Select item 2001982571.

Functional reprogramming of monocytes in acute and convalescent severe COVID-19 patients

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL24676
64 Samples

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Accession:: GSE198257

ID:: 200198257

PubMed Full text in PMC Similar studies

Select item 2001982552.

Functional reprogramming of monocytes in acute and convalescent severe COVID-19 patients [ATAC-seq]

(Submitter supplied) Severe COVID-19 disease is associated with dysregulation of the myeloid compartment during acute infection. Survivors frequently experience long-lasting sequelae but little is known about the eventual persistence of this immune alteration. Herein, we evaluated Toll-like receptor-induced cytokine responses in a cohort of mild to critical patients during acute or convalescent phases (n=97). In the acute phase, we observed impaired cytokine production by monocytes in the most severe patients. more...