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Items: 3

1.

ADAR1 utilizes independent mechanisms to suppress MDA5 and PKR activation by cellular double-stranded RNA

(Submitter supplied) The antiviral defense in vertebrates requires the innate immune system to sense foreign “non-self” nucleic acids while avoiding “self” nucleic acids, which is accomplished by an intricate system. Cellular double-stranded RNAs (dsRNAs) are edited by the RNA editing enzyme ADAR1 to prevent their dsRNA structure pattern from being recognized as viral dsRNA. Lack of RNA editing by ADAR1 enables activation of MDA5, a cytosolic dsRNA sensor, by cellular dsRNA. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL20301 GPL21697
17 Samples
Download data: CSV, TXT
Series
Accession:
GSE198386
ID:
200198386
2.

NextSeq 550 (Homo sapiens)

Platform
Accession:
GPL21697
ID:
100021697
3.

HEK293T_WT_1

Organism:
Homo sapiens
Source name:
HEK293T
Platform:
GPL21697
Series:
GSE198386
Download data
Sample
Accession:
GSM5946006
ID:
305946006
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db=gds|term=GSM5946006[Accession]|query=1|qty=2|blobid=MCID_67b1b9305b08ab4a1726dbc3|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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