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Items: 3

1.

G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes

(Submitter supplied) G-quadruplexes (G4s) are unique noncanonical nucleic acid secondary structures, which could interact with transcription factors and chromatin remodelers to regulate cell type-specific transcriptome and shape chromatin landscapes. Based on the direct interactions between G4 and natural porphyrins, we established an in situ capture sequencing approach combining synthesized biotin-PEG4-Hemin and Cleavage Under Targets and Tagmentation (CUT&Tag) strategy to profile the Hemin binding sites in the human genome. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL24676 GPL24247
48 Samples
Download data: BW
Series
Accession:
GSE198658
ID:
200198658
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

293T-R-loop-CUT-Tag-CTRL

Organism:
Homo sapiens
Source name:
R-Loop CUT&Tag analysis with 2HBD
Platform:
GPL24676
Series:
GSE198658
Download data: BW
Sample
Accession:
GSM5954452
ID:
305954452
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