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Items: 3

1.

Temporal perturbation of histone deacetylase activity reveals a requirement for HDACs 1-3 in mes-endoderm cell differentiation

(Submitter supplied) We investigate the genome-wide chromatin landscape during mes-endoderm and cardiac progenitor specification to reveal dynamic changes to chromatin accessibility upon HDAC1-3 inhibition. To evaluate the changes to chromatin accessibility upon inhibition of HDACs 1-3 during cardiac lineage specification, we performed ATAC-seq using the Omni-ATAC protocol (Corces et al., 2017) on Day 5 differentiated hiPSCs treated for 48 hours using small molecule HDAC inhibitors with isozyme selectivity
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
9 Samples
Download data: BED, BW, GTF, TXT
Series
Accession:
GSE200808
ID:
200200808
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

Replicate 2; BRD4884 treated Day 5 differentiated hiPSCs

Organism:
Homo sapiens
Source name:
WTC CRISPRi GCaMP hiPSC (RRID CVCL_VM38)
Platform:
GPL24676
Series:
GSE200808
Download data: BW, TXT
Sample
Accession:
GSM6043948
ID:
306043948
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db=gds|term=GSM6043948[Accession]|query=1|qty=2|blobid=MCID_66df91a0fadf6d74e12b39df|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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