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Items: 3

1.

Single Nuclei RNA-Seq to map progression of non-alcoholic fatty liver disease (NAFLD) in patients II

(Submitter supplied) Non-alcoholic fatty liver disease (NAFLD) is of increasing prevalence and concern. NAFLD can progress to non-alcoholic steatohepatitis (NASH), to cirrhosis and finally to end-stage liver disease where liver transplantation is required. We aimed to characterise this progression by performing single nuclei transcriptomic analysis of liver biopsies taken from patients across the disease spectrum. We have observed that hepatocytes are the cell type affected mostly by the disease and describe plasticity between cell types which may represent a regenerative process.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
59 Samples
Download data: CSV
Series
Accession:
GSE202379
ID:
200202379
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

P49-NASH w/o cirrhosis-D-SITTA9

Organism:
Homo sapiens
Source name:
liver biopsy
Platform:
GPL24676
Series:
GSE202379
Download data: CSV
Sample
Accession:
GSM6112224
ID:
306112224
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