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Items: 4

1.

Melanoma GEMM Tumors, untreated or vemurafenib treated [bulk RNA-seq]

(Submitter supplied) Emerging research suggests that multiple tumor compartments can influence treatment responsiveness and relapse, yet the search for therapeutic resistance mechanisms remains largely focused on acquired genomic alterations in cancer cells. Here, we show how treatment-induced changes occur in multiple tumor compartments during tumor relapse and can reduce benefit of follow-on therapies. By utilizing serial biopsies, next generation sequencing and single cell transcriptomics, we tracked the evolution of multiple cellular compartments within individual lesions during first-line treatment response, relapse and second-line therapeutic interventions in an autochthonous model of melanoma. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
34 Samples
Download data: TSV
Series
Accession:
GSE205251
ID:
200205251
2.

Melanoma GEMM Tumors, untreated or vemurafenib treated

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21103 GPL17021
37 Samples
Download data: TXT
Series
Accession:
GSE205294
ID:
200205294
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

SAM17356772

Organism:
Mus musculus
Source name:
skin
Platform:
GPL17021
Series:
GSE205251 GSE205294
Download data
Sample
Accession:
GSM6209165
ID:
306209165
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Supplemental Content

db=gds|term=GSM6209165[Accession]|query=1|qty=2|blobid=MCID_6691d1f149fc8a23250492c4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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