GSM641822[Accession] - GEO DataSets

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Items: 4

Select item 2000261411.

Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL9052
41 Samples

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Series

Accession:: GSE26141

ID:: 200026141

PubMed Full text in PMC Similar studies

Select item 2000261372.

Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium [ChIP-Seq]

(Submitter supplied) Here we describe the application of high-throughput sequencing technology for profiling histone and DNA methylation, and gene expression patterns of normal human mammary progenitor-enriched and luminal lineage-committed cells. We observed significant differences in histone H3 lysine 27 tri-methylation (H3K27me3) enrichment and DNA methylation of genes expressed in a cell type-specific manner, suggesting their regulation by epigenetic mechanisms and a dynamic interplay between the two processes that together define developmental potential. more...