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Items: 3

1.

Epigenetic regulation of profibrotic macrophages in systemic sclerosis- associated interstitial lung disease

(Submitter supplied) Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is the leading cause of death in patients with systemic sclerosis (SSc) with unclear pathogenesis and limited treatment options. Evidence strongly supports an important role for profibrotic, SPP1-expressing macrophages in SSc-ILD. We sought to define the transcriptome and chromatin structural changes of SPP1 SSc-ILD macrophages, so as to better understand their role in promoting fibrosis and to identify transcription factors associated with open chromatin driving their altered phenotype.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
17 Samples
Download data: BAI, BED, CSV, H5, TBI, TSV
Series
Accession:
GSE212109
ID:
200212109
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

SC313 2019-095-CORE

Organism:
Homo sapiens
Source name:
Lung
Platform:
GPL24676
Series:
GSE212109
Download data: H5
Sample
Accession:
GSM6509492
ID:
306509492
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db=gds|term=GSM6509492[Accession]|query=1|qty=2|blobid=MCID_67af98b55b08ab4a17e51b39|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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