GSM6583412[Accession] - GEO DataSets

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Items: 4

Select item 2002133831.

Mechanistic divergence of piRNA biogenesis in Drosophila

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Drosophila melanogaster; Drosophila mojavensis; Drosophila pseudoobscura; Drosophila bifasciata; Drosophila eugracilis

Type:: Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

5 related Platforms
27 Samples

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Accession:: GSE213383

ID:: 200213383

Select item 2002133692.

Mechanistic divergence of piRNA biogenesis in Drosophila [ncRNA-seq]

(Submitter supplied) Organisms require mechanisms to distinguish self and non-self RNA. This distinction is crucial to initiate the biogenesis of piRNAs. In Drosophila ovaries, PIWI-guided slicing and the recognition of piRNA precursor transcripts by the DEAD-box RNA helicase Yb are the two known mechanisms to initiate biogenesis in the germline and the soma, respectively. Both, the PIWI proteins and Yb are highly conserved across most Drosophila species and are thought to be essential to the piRNA pathway and for silencing TEs. more...