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Items: 4

1.

Spic regulates one-carbon metabolism and histone methylation in ground-state pluripotency

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17021
34 Samples
Download data: BEDGRAPH, BW
Series
Accession:
GSE222058
ID:
200222058
2.

(ATAC-seq_and_ChIP-seq) Spic regulates one-carbon metabolism and histone methylation in ground-state pluripotency

(Submitter supplied) Understanding mechanisms of epigenetic regulation in embryonic stem cells (ESCs) is of fundamental importance for stem cell and developmental biology. Here we identify Spic, a member of the ETS family of transcription factors, as a specific marker of ground state pluripotency. We show that Spic is rapidly induced in ESCs cultured with GSK3-, MEK-inhibitors and LIF (2iL), and in response to MEK/ERK inhibition. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL17021
24 Samples
Download data: BW, TXT, XLSX
Series
Accession:
GSE222057
ID:
200222057
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

Spic-ChIP-seq-OE12-2iLd3

Organism:
Mus musculus
Source name:
embryonic
Platform:
GPL17021
Series:
GSE222057 GSE222058
Download data: BW
Sample
Accession:
GSM6913982
ID:
306913982
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Supplemental Content

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