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Items: 4

1.

SATB2 organizes the 3D genome architecture of cognition in cortical neurons

(Submitter supplied) The DNA-binding protein SATB2 is genetically linked to human intelligence. We studied its influence on 3D epigenome by mapping chromatin interactions and accessibility in control versus SATB2-deficient cortical neurons. We find that SATB2 affects the chromatin looping between enhancers and promoters of neuronal activity-regulated genes, thus influencing their expression. It also alters A/B compartments, Topologically Associating Domains and Frequently Interacting Regions. more...
Organism:
Mus musculus
Type:
Other; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL17021
34 Samples
Download data
Series
Accession:
GSE222609
ID:
200222609

PubMed Similar studies

2.

SATB2 organizes the 3D genome architecture of cognition in cortical neurons [Hi-C]

(Submitter supplied) The DNA-binding protein SATB2 is genetically linked to human intelligence. We studied its influence on 3D epigenome by mapping chromatin interactions and accessibility in control versus SATB2-deficient cortical neurons. We find that SATB2 affects the chromatin looping between enhancers and promoters of neuronal activity-regulated genes, thus influencing their expression. It also alters A/B compartments, Topologically Associating Domains and Frequently Interacting Regions. more...
Organism:
Mus musculus
Type:
Other
Platforms:
GPL17021 GPL24247
12 Samples
Download data: BEDGRAPH, BEDPE, TXT
Series
Accession:
GSE222606
ID:
200222606

PubMed Similar studies

3.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
13930 Series
690072 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

4.

HiC_Flx1: Satb2 flx/flx DIV14 primary cortical cultures, 1h bic, rep1

Organism:
Mus musculus
Source name:
Cortex
Platform:
GPL24247
Series:
GSE222606 GSE222609
Download data
Sample
Accession:
GSM6927709
ID:
306927709

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db=gds|term=GSM6927709[Accession]|query=1|qty=2|blobid=MCID_670e2c7fc7d3ca20d5e1f01d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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