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Items: 4

1.

TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions [Mouse Methylation285 12v1-0 BeadChip]

(Submitter supplied) DNA methylation erasure is required for mammalian primordial germ cell reprogramming. TET enzymes iteratively oxidize 5-methylcytosine to generate 5-hyroxymethylcytosine (5hmC), 5-formylcytosine, and 5-carboxycytosine to facilitate active genome demethylation. Whether these bases are required to promote replication-coupled dilution or activate base excision repair during germline reprogramming remains unresolved due to the lack of genetic models that decouple TET1 activities. more...
Organism:
Mus musculus
Type:
Methylation profiling by genome tiling array
Platform:
GPL31950
36 Samples
Download data: CSV, IDAT, XLSX
Series
Accession:
GSE224349
ID:
200224349
2.

TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by genome tiling array
Platforms:
GPL31950 GPL32159 GPL21103
63 Samples
Download data: BEDGRAPH, BW, CSV, IDAT, NARROWPEAK
Series
Accession:
GSE224459
ID:
200224459
3.

Infinium MouseMethylation285 BeadChip

(Submitter supplied) https://support.illumina.com//array/array_kits/infinium-mouse-methylation-beadchip-kit.html
Organism:
Mus musculus
23 Series
518 Samples
Download data
Platform
Accession:
GPL31950
ID:
100031950
4.

genomic DNA from Tet1-KO sperm 8

Organism:
Mus musculus
Source name:
KO sperm
Platform:
GPL31950
Series:
GSE224349 GSE224459
Download data: CSV, IDAT
Sample
Accession:
GSM7020172
ID:
307020172
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Supplemental Content

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