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Items: 4

1.

Lactate-dependent Transcriptional Regulation Controls Mammalian Eye Morphogenesis [H3K27ac ChIP-seq]

(Submitter supplied) Mammalian retinal metabolism favors aerobic glycolysis. However, the role of glycolytic metabolism in retinal morphogenesis remains unknown. We report that aerobic glycolysis is necessary for the early stages of retinal development. Taking advantage of an unbiased approach that combines the use of eye organoids and single-cell RNA sequencing, we identify specific glucose transporters and glycolytic genes in retinal progenitors. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21103
8 Samples
Download data: BIGWIG
Series
Accession:
GSE224648
ID:
200224648
2.

Lactate-dependent Transcriptional Regulation Controls Mammalian Eye Morphogenesis.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platform:
GPL21103
22 Samples
Download data: BIGWIG, MTX, TSV, TXT
Series
Accession:
GSE202759
ID:
200202759
3.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
4.

Rax-GFP ESCs, H3K27ac antagonist Rep 2

Organism:
Mus musculus
Source name:
ESC-derived eye organoids (Rax-GFP ESCs)
Platform:
GPL21103
Series:
GSE202759 GSE224648
Download data: BIGWIG
Sample
Accession:
GSM7029062
ID:
307029062
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Supplemental Content

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