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Items: 4

1.

Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Other; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL19057 GPL21103
170 Samples
Download data: BEDGRAPH, BIGWIG, COOL, NARROWPEAK, TXT
Series
Accession:
GSE205783
ID:
200205783
2.

Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos [ChIP-seq]

(Submitter supplied) During development, Hox genes are activated in a time sequence following their relative positions on their clusters, leading to the proper identities of structures along the rostral to caudal axis. To understand the mechanism operating this Hox timer, we used ES-cells derived stembryos and show that the core of the process involves the start of transcription at the anterior part of the cluster, following Wnt signaling, and a concomitant loading of cohesin complexes enriched on the transcribed DNA segments, i.e., with an asymmetric distribution in favor of the anterior part the gene cluster. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19057
82 Samples
Download data: BEDGRAPH, BIGWIG, NARROWPEAK
Series
Accession:
GSE205779
ID:
200205779
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

wt_48h_RAD21_rep1

Organism:
Mus musculus
Source name:
stembryo
Platform:
GPL19057
Series:
GSE205779 GSE205783
Download data: BIGWIG, NARROWPEAK
Sample
Accession:
GSM7035385
ID:
307035385
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