U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 4

1.

RIF1 regulates early replication timing in murine B cells.

(Submitter supplied) The mammalian DNA replication timing (RT) program is crucial for the proper functioning and integrity of the genome. The best-known mechanism for controlling RT is the suppression of late origins of replication in heterochromatin by RIF1. Here, we report that in antigen-activated, hypermutating murine B lymphocytes, RIF1 binds predominantly to early-replicating active chromatin and promotes early replication, but plays a minor role in regulating replication origin activity, gene expression and genome organization in B cells. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other
4 related Platforms
69 Samples
Download data: BEDGRAPH, BW, HIC, MCOOL
Series
Accession:
GSE228880
ID:
200228880
2.

RIF1 regulates replication origin activity and early replication timing in B cells [HI-C]

(Submitter supplied) The mammalian DNA replication timing (RT) program is crucial for the proper functioning and integrity of the genome. The best-known mechanism for controlling RT is the suppression of late origins of replication in heterochromatin by RIF1. Here, we report that in antigen-activated, hypermutating B lymphocytes, RIF1 binds predominantly to early-replicating active chromatin, regulates early origin firing and promotes early replication. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL24247
2 Samples
Download data: BEDGRAPH, BW, HIC, MCOOL
Series
Accession:
GSE228876
ID:
200228876
3.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
4.

CH12_HiC_Rif1KO_shMcm6

Organism:
Mus musculus
Source name:
CH12
Platform:
GPL24247
Series:
GSE228876 GSE228880
Download data: BEDGRAPH, BW, HIC, MCOOL
Sample
Accession:
GSM7140987
ID:
307140987
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSM7140987[Accession]|query=1|qty=2|blobid=MCID_665774cbe795547e5ff3a77b|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center