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Items: 3

1.

Loss of the Atrial Fibrillation-related gene, Zfhx3, Results in Atrial Dilation and Arrhythmias by Disruption of Genes Essential for Cardiovascular Homeostasis

(Submitter supplied) Background: ZFHX3, a gene that encodes a large transcription factor, is the second-most significantly associated locus with AF, but its function in the heart is unknown. This study aims to identify causative genetic variation related to AF at the ZFHX3 locus and examine the impact of Zfhx3 loss on cardiac function in mice. Methods: CRISPR-Cas9 genome editing, chromatin immunoprecipitation, and luciferase assays in pluripotent stem cell-derived cardiomyocytes were used to identify causative genetic variation related to AF at the ZFHX3 locus. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
18 Samples
Download data: TXT
Series
Accession:
GSE229525
ID:
200229525

PubMed Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Mus musculus)

Organism:
Mus musculus
13796 Series
688519 Samples
Download data
Platform
Accession:
GPL24247
ID:
100024247

3.

k921_KO_RA

Organism:
Mus musculus
Source name:
right atria
Platform:
GPL24247
Series:
GSE229525
Download data
Sample
Accession:
GSM7164923
ID:
307164923

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db=gds|term=GSM7164923[Accession]|query=1|qty=2|blobid=MCID_6705a6f791df3b340a7e33d2|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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