GSM7439154[Accession] - GEO DataSets

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Items: 4

Select item 2002339261.

Identification of cardiac developmental toxicants in differentiated human induced pluripotent stem cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
69 Samples

Download data: CEL

Series

Accession:: GSE233926

ID:: 200233926

Analyze with GEO2R

Select item 2002339242.

Identification of cardiac developmental toxicants in differentiated human induced pluripotent stem cells [Toxicants]

(Submitter supplied) Animal studies for embryotoxicity evaluation of potential therapeutics and environmental factors are complex, costly, and time-consuming. Often, studies are not of human relevance because of species differences. In the present study, we recapitulated the process of cardiomyogenesis in human induced pluripotent stem cells (hiPSCs) by modulation of the Wnt signaling pathway to identify a key cardiomyogenesis gene signature that can be applied to identify compounds and/or stress factors compromising the cardiomyogenesis process. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
57 Samples

Download data: CEL

Series

Accession:: GSE233924

ID:: 200233924

Analyze with GEO2R

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...