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Items: 3

1.

Cas-SF01, an engineered Cas12i nuclease is an efficient genome editing tool in mammalian cells and plants

(Submitter supplied) The type V-I CRISPR-Cas system is becoming increasingly attractive for its potential utility in gene editing. However, natural nucleases often exhibit low efficiency, limiting their application. Here, we utilized structure-guided rational design and combinatorial protein engineering to optimize an uncharacterized Cas12i nuclease, Cas12i3. Accordingly, we developed Cas-SF01, a Cas12i3 variant that exhibits significantly improved gene-editing activity in mammalian cells and plants. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL24676
8 Samples
Download data: TXT
Series
Accession:
GSE236755
ID:
200236755

PubMed Full text in PMC Similar studies

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
16169 Series
916461 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

293T,3days, rep2_2

Organism:
Homo sapiens
Source name:
HEK293T
Platform:
GPL24676
Series:
GSE236755
Download data: TXT
Sample
Accession:
GSM7575049
ID:
307575049

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db=gds|term=GSM7575049[Accession]|query=1|qty=2|blobid=MCID_66e34c31b3438a05766d0cc0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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