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Items: 4

1.

Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL24517 GPL26853
37 Samples
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Series
Accession:
GSE236905
ID:
200236905
2.

Integrated single-cell multiomics uncovers foundational regulatory mechanisms of lens development and pathology [CUT&RUN]

(Submitter supplied) Ocular lens development entails epithelial to fiber cell differentiation, defects in which cause congenital cataract. We report the first single-cell multiomic atlas of lens development, leveraging snRNA-seq, snATAC-seq, and CUT&RUN-seq to discover novel mechanisms of cell fate determination and cataract-linked regulatory networks. A comprehensive profile of cis- and trans-regulatory interactions, including for the cataract-linked transcription factor MAF, is established across a temporal trajectory of fiber cell differentiation. more...
Organism:
Gallus gallus
Type:
Other
Platform:
GPL24517
20 Samples
Download data: NARROWPEAK
Series
Accession:
GSE236904
ID:
200236904
3.

HiSeq X Ten (Gallus gallus)

Organism:
Gallus gallus
45 Series
555 Samples
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Platform
Accession:
GPL24517
ID:
100024517
4.

H3K4me3_3

Organism:
Gallus gallus
Source name:
Lens
Platform:
GPL24517
Series:
GSE236904 GSE236905
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Sample
Accession:
GSM7585112
ID:
307585112
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Supplemental Content

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