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Items: 3

1.

Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis

(Submitter supplied) N6‐Methyladenosine (m6A) is the most abundant internal post‐translational modification, and its contribution to cancer evolution has recently been appreciated. Renal cancer is the most common adult genitourinary cancer, of which ~85% is accounted for by the clear cell subtype (ccRCC) characterized by VHL loss. In this study, we demonstrate for the first time that VHL binds with m6A enzymatic complex proteins and promotes METTL3-METTL14 complex formation, and VHL depletion suppresses mRNA m6A modification. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL18573
21 Samples
Download data: BW, XLSX
Series
Accession:
GSE239892
ID:
200239892

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12375 Series
338370 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

HKC_sgCtrl_RNA_Rep3

Organism:
Homo sapiens
Source name:
HKC
Platform:
GPL18573
Series:
GSE239892
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Sample
Accession:
GSM7676719
ID:
307676719

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db=gds|term=GSM7676719[Accession]|query=1|qty=2|blobid=MCID_66dec5c6ebdbf01cbf649d98|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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