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Items: 3

1.

Inhibitory effect of VNLG-152R on breast cancer cells MDA-MB-231

(Submitter supplied) In previous studies, our research demonstrated that VNLG-152R exhibits inhibitory effects on Triple Negative Breast Cancer (TNBC) cells both in vitro and in vivo. The TNBC cell line MDA-MB-231 cells were treated with VNLG-152R. A total of 337 genes were differentially expressed when MDA-MB-231 cells were treated with 10 μM VNLG-152R for 24h; 259 genes were upregulated and 78 downregulated. Through proteome analyses, we discovered that VNLG-152R upregulates the expression of E3 ligase Synoviolin 1 (SYVN1), also called 3-hydroxy-3-methylglutaryl reductase degradation (HRD1) in TNBC cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
6 Samples
Download data: COUNTS
Series
Accession:
GSE242514
ID:
200242514
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

VNLG152_MDA_MB231_rep2

Organism:
Homo sapiens
Source name:
Cell line drived from breast cancer tissue
Platform:
GPL24676
Series:
GSE242514
Download data: COUNTS
Sample
Accession:
GSM7764790
ID:
307764790
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db=gds|term=GSM7764790[Accession]|query=1|qty=2|blobid=MCID_661b71366bc2bd5af4bbb385|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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