GSM7770903[Accession] - GEO DataSets

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Items: 4

Select item 2002428091.

MicroRNA-mediated attenuation of branched-chain amino acid catabolism promotes ferroptosis in chronic kidney disease.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Other; Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL19057
24 Samples

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Series

Accession:: GSE242809

ID:: 200242809

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Select item 2002428062.

MicroRNA-mediated attenuation of branched-chain amino acid catabolism promotes ferroptosis in chronic kidney disease [CLIP-seq]

(Submitter supplied) Chronic kidney disease (CKD) complicates cisplatin-based chemotherapy of cancer patients. Here we investigate microRNA (miRNA)-regulated transcriptomic activity to unveil biological processes associated with cisplatin-induced kidney injury. Implementing chimeric-eCLIP-seq approach to a mouse model for cisplatin-induced CKD, we identify direct pairs of miRNA and their target messenger RNA in the injured kidney. more...