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Items: 4

1.

ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL20301 GPL16791
64 Samples
Download data: MTX, TSV
Series
Accession:
GSE243569
ID:
200243569
2.

ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts [Cell Line ATAC-seq]

(Submitter supplied) The majority of EGFR mutant lung adenocarcinomas respond well to EGFR tyrosine kinase inhibitors (TKIs). However, most of these responses are partial with drug tolerant residual disease remaining even at the time of maximal response. This residual disease ultimately leads to relapses which eventually develop in most patients. To investigate the cellular and molecular properties of residual tumor cells in vivo, we leveraged patient-derived models of EGFR mutant lung cancer. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL20301
18 Samples
Download data: BW
Series
Accession:
GSE243568
ID:
200243568
3.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
4.

PC9ASCL1, vehicle, rep2

Organism:
Homo sapiens
Source name:
PC9
Platform:
GPL20301
Series:
GSE243568 GSE243569
Download data
Sample
Accession:
GSM7791184
ID:
307791184
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db=gds|term=GSM7791184[Accession]|query=1|qty=2|blobid=MCID_67a84d2b85cceb19951d6a62|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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