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Items: 3

1.

Development of a novel guinea pig model producing transgenerational endothelial transcriptional changes driven by maternal food restriction and a second metabolic insult of high-fat diet.

(Submitter supplied) Developmental programming of chronic adverse cardiovascular health outcomes has been studied both using numerous human populations and an array of animal models. However, the mechanisms that produce transgenerational effects have been difficult to study due to a lack of developmentally relevant models. As such, how increased disease risk is carried to the second generation has been poorly studied. We hypothesized that the endothelium which mediates many acute and chronic vascular inflammatory responses is a key player in these effects, and epidemiological studies implicate transgenerational nutritional effects on endothelial health. more...
Organism:
Cavia porcellus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28437
24 Samples
Download data: CSV, XLSX
Series
Accession:
GSE244302
ID:
200244302
2.

Illumina NovaSeq 6000 (Cavia porcellus)

Organism:
Cavia porcellus
14 Series
255 Samples
Download data
Platform
Accession:
GPL28437
ID:
100028437
3.

F1, 100% ad lib, High Fat GP16.021

Organism:
Cavia porcellus
Source name:
Carotid artery
Platform:
GPL28437
Series:
GSE244302
Download data
Sample
Accession:
GSM7813182
ID:
307813182
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db=gds|term=GSM7813182[Accession]|query=1|qty=2|blobid=MCID_67538aaf79392954d41f373b|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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