GSM7833089[Accession] - GEO DataSets

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Items: 4

Select item 2002449841.

Molecular patterns of resistance to immune checkpoint blockade in melanoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL34293 GPL18573 GPL24676
78 Samples

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Accession:: GSE244984

ID:: 200244984

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2002449822.

Molecular patterns of resistance to immune checkpoint blockade in melanoma [bulk RNA-Seq]

(Submitter supplied) Immune checkpoint blockade (ICB) has improved outcome for patients with metastatic melanoma but not all benefit from treatment. Several immune- and tumor intrinsic features are associated with clinical response at baseline. However, we need to further understand the molecular changes occurring during development of ICB resistance. Here, we collected biopsies from a cohort of 44 melanoma patients after progression to anti-CTLA4 or anti-PD1 monotherapy. more...