GSM7919741[Accession] - GEO DataSets

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Items: 4

Select item 2002487781.

COVID-19 and influenza infections mediate distinct pulmonary cellular and transcriptomic changes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Third-party reanalysis

Platform:: GPL30172
24 Samples

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Series

Accession:: GSE248778

ID:: 200248778

PubMed Full text in PMC Similar studies

Select item 2002487732.

COVID-19 and influenza infections mediate distinct pulmonary cellular and transcriptomic changes [RNA-seq]

(Submitter supplied) SARS-CoV-2 infection can cause persistent respiratory sequelae, as seen in long COVID. However, the underlying mechanisms remain unclear. To investigate pulmonary cellular and transcriptomic changes mediated by SARS-CoV-2 and influenza infection, we characterized the SARS-CoV-2-infected K18-hACE2 (K18) mice and compared their lung recovery with a mouse-adapted influenza model and verified the finding in SARS-CoV-2-infected nonhuman primates and in fatal human COVID-19 cases. more...