GSM7989813[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2002519051.

Mitochondrial complex I promotes kidney cancer metastasis

(Submitter supplied) Most kidney cancers display metabolic dysfunction but how this relates to cancer progression in humans is unknown. We infused 13C-labeled nutrients during surgical tumour resection in over 80 patients with kidney cancer. Labeling from [U-13C]glucose varies across subtypes, indicating that the kidney environment alone cannot account for all metabolic reprogramming in these tumours. Compared to the adjacent kidney, clear cell renal cell carcinomas (ccRCC) display suppressed labelling of tricarboxylic acid (TCA) cycle intermediates in vivo and in organotypic cultures ex vivo, indicating that suppressed labeling is tissue intrinsic. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18573
123 Samples

Download data: XLSX

Series

Accession:: GSE251905

ID:: 200251905

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000185732.

Illumina NextSeq 500 (Homo sapiens)

Organism:: Homo sapiens

12466 Series
340425 Samples

Platform

Accession:: GPL18573

ID:: 100018573

Select item 3079898133.

Matched_DB1 Metastasis ccRCC

Organism:: Homo sapiens

Source name:: ccRCC Metastasis

Platform:: GPL18573
Series:: GSE251905

Sample

Accession:: GSM7989813

ID:: 307989813

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GSM7989813[Accession] (3)
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