GSM7996651[Accession] - GEO DataSets

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Items: 3

Select item 2002522051.

RORγt -expressing FOXP3+ skin-resident Treg cells derived from the periphery in Allergen-Specific Immunotherapy

(Submitter supplied) The study explored the impact of Specific Immunotherapy on patients with Atopic Dermatitis sensitized to house dust mites by analyzing the transcriptomes of T regulatory cells before and after treatment. Result found that effective SIT is associated with distinct gene expression changes in Treg cells, particularly increased expression of Treg markers and RORC, a gene linked to immune regulation. These results indicate that successful SIT may enhance the function of Treg cells expressed RORC and help restore immune balance in these patients.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL16686
12 Samples

Download data: CEL

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Accession:: GSE252205

ID:: 200252205

Analyze with GEO2R

Select item 1000166862.

[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html November 15, 2012: HuGene-2_0-st-v1.na33.hg19.transcript.csv Protocol: See manufacturer's web site