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Items: 3

1.

Physical interaction with Spo11 mediates the localisation of Mre11 to chromatin in meiosis and promotes its nuclease activity

(Submitter supplied) Meiotic recombination is of central importance for the proper segregation of homologous chromosomes and is initiated by DNA double-strand breaks (DSB) that depend on Spo11 and Mre11. Calibrated chromatin immunoprecipitation (ChIP) for Mre11 shows that Spo11 promotes Mre11 recruitment to chromatin, independent of DSB formation. A C-terminal deletion mutant deficient in Spo11 interaction severely reduces the association of Mre11 with meiotic chromatin. more...
Organism:
Nakaseomyces glabratus; Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL34086
12 Samples
Download data: TXT, XLSX
Series
Accession:
GSE253302
ID:
200253302
2.

Illumina HiSeq 2500 (Nakaseomyces glabratus; Saccharomyces cerevisiae)

Organism:
Saccharomyces cerevisiae; Nakaseomyces glabratus
1 Series
12 Samples
Download data
Platform
Accession:
GPL34086
ID:
100034086
3.

spo11-Y135F Mre11-HA6 t5 WCE

Organism:
Saccharomyces cerevisiae; Nakaseomyces glabratus
Source name:
meiotic yeast cells
Platform:
GPL34086
Series:
GSE253302
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Sample
Accession:
GSM8017947
ID:
308017947
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Supplemental Content

db=gds|term=GSM8017947[Accession]|query=1|qty=3|blobid=MCID_67573127fd45205cc532494e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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