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Items: 4

1.

Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased binding affinity to Fcg receptors during acute SHIV infection shapes innate and adaptive cellular immunity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Macaca mulatta
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL27943 GPL23949
566 Samples
Download data: TXT
Series
Accession:
GSE254837
ID:
200254837
2.

Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased binding affinity to Fcg receptors during acute SHIV infection shapes innate and adaptive cellular immunity [set1]

(Submitter supplied) Anti-HIV-1 broadly neutralizing antibodies (bNAbs) have the dual potential of mediating virus neutralization and antiviral effector functions through their Fab and Fc domains, respectively. So far, bNAbs with enhanced Fc effector functions in vitro have only been tested in NHPs during chronic simian-HIV (SHIV) infection. Here, we investigated the effects of administering in acute SHIVAD8-EO infection either wild-type (WT) bNAbs or bNAbs carrying the S239D/I332E/A330L (DEL) mutation, which increases binding to FcgRs. more...
Organism:
Macaca mulatta
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23949
175 Samples
Download data: TXT
Series
Accession:
GSE254781
ID:
200254781
3.

Illumina HiSeq 4000 (Macaca mulatta)

Organism:
Macaca mulatta
49 Series
1725 Samples
Download data
Platform
Accession:
GPL23949
ID:
100023949
4.

DGBG_D14_pDCs

Organism:
Macaca mulatta
Source name:
lymph node
Platform:
GPL23949
Series:
GSE254781 GSE254837
Download data: TXT
Sample
Accession:
GSM8057583
ID:
308057583
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