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Items: 3

1.

AMAR-seq: automated multimodal sequencing of DNA methylation, chromatin accessibility, and RNA expression with single-cell resolution

(Submitter supplied) Parallel single-cell multimodal sequencing is the most intuitive and precise tool for cellular status research. In this study, we propose AMAR-seq to automate methylation, chromatin accessibility and RNA sequencing on a chip with single-cell precision. We validated the accuracy and robustness of AMAR-seq in comparison with standard single-omics methods. The high gene detection rate and genome coverage of AMAR-seq enabled us to establish a genome-wide gene expression regulatory atlas, implement single-cell copy number variation analysis, and construct a single-gene, single-base resolution gene expression, DNA methylation, and chromatin accessibility landscape. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Other
Platforms:
GPL24676 GPL24247
83 Samples
Download data: COV, TXT
Series
Accession:
GSE261788
ID:
200261788
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

mESC_0d_RNA_2

Organism:
Mus musculus
Source name:
E14, 129/Ola
Platform:
GPL24247
Series:
GSE261788
Download data: TXT
Sample
Accession:
GSM8152011
ID:
308152011
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