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Items: 3

1.

Planar cell polarity proteins mediate ketamine-induced restoration of glutamatergic synapses in prefrontal cortical neurons in a mouse model for chronic stress

(Submitter supplied) We performed single cell transcriptomics analyses in medial prefrontal cortical (mPFC) and basolateral amygdala (BLA). Ketamine induced changes in inflammatory pathways reversing corticosterone effects. Cell-cell communication analyses predicted that planar-cell-polarity (PCP) signaling is decreased after corticosterone but increased following ketamine administration in excitatory neurons. Single cell transcriptomics analyses in dorsolateral prefrontal cortical (dl-PFC) neurons of depressed patients also showed decreased PCP signaling in excitatory neurons. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
20 Samples
Download data: MTX, TAR, TSV
Series
Accession:
GSE191016
ID:
200191016
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

CORT-Ket (#9968-2)

Organism:
Mus musculus
Source name:
Brain (BLA)
Platform:
GPL24247
Series:
GSE191016
Download data: MTX, TSV
Sample
Accession:
GSM8231215
ID:
308231215
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db=gds|term=GSM8231215[Accession]|query=1|qty=2|blobid=MCID_66d271edb1cb767cd2f753d5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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