GSM857395[Accession] - GEO DataSets

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Items: 4

Select item 2000349081.

Genetic and epigenetic determinants of neurogenesis and myogenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL11002 GPL1261 GPL9250
33 Samples

Download data: BAM, BEDGRAPH, CEL, MAP

Series

Accession:: GSE34908

ID:: 200034908

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000349062.

Genetic and epigenetic determinants of neurogenesis and myogenesis [ChIP-seq]

(Submitter supplied) The regulatory networks of differentiation programs have been partly characterized; however, the molecular mechanisms of lineage-specific gene regulation by highly similar transcription factors remain largely unknown. Here we compare the genome-wide binding and transcription profiles of NEUROD2-mediated neurogenesis with MYOD-mediated myogenesis. We demonstrate that NEUROD2 and MYOD bind a shared CAGCTG E-box motif and E-box motifs specific for each factor: CAGGTG for MYOD and CAGATG for NEUROD2. more...