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Items: 4

1.

Hierarchical regulation in a KRAS pathway-dependent transcriptional network revealed by a reverse-engineering approach

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL10741
18 Samples
Download data: CEL
Series
Accession:
GSE38614
ID:
200038614
2.

Hierarchical regulation in a KRAS pathway-dependent transcriptional network revealed by a reverse-engineering approach (7TF and control)

(Submitter supplied) RAS mutations are highly relevant for progression and therapy response of human tumours, but the genetic network that ultimately executes the oncogenic effects is poorly understood. Here we used a reverse-engineering approach in an ovarian cancer model to reconstruct KRAS oncogene-dependent cytoplasmic and transcriptional networks from perturbation experiments based on gene silencing and pathway inhibitor treatments. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL10741
16 Samples
Download data: CEL
Series
Accession:
GSE38584
ID:
200038584
3.

[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [probe set (exon) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html #%create_date=Tue Dec 8 17:34:30 2009 PST #%chip_type=RaGene-1_0-st-v1 #%lib_set_name=RaGene-1_0-st #%lib_set_version=v1 #%genome-species=Rattus norvegicus #%genome-version=rn4 #%genome-version-ucsc=rn4 #%genome-version-ncbi=HGSC v3.4 #%genome-version-create_date=2004-11 #%netaffx-annotation-date=2009-11-16 #%netaffx-annotation-netaffx-build=30.1 Protocol: See manufacturer's web site
Organism:
Rattus norvegicus
8 Series
76 Samples
Download data
Platform
Accession:
GPL10741
ID:
100010741
4.

RAS-ROSE cells treated with Klf6 siRNA 2

Organism:
Rattus norvegicus
Source name:
Klf6_siRNA2
Platform:
GPL10741
Series:
GSE38584 GSE38614
Download data: CEL
Sample
Accession:
GSM945787
ID:
300945787
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