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Items: 4

1.

Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [SNP]

(Submitter supplied) Basal-like and luminal breast tumors have distinct clinical behavior and molecular profiles, yet the underlying mechanisms are poorly defined. To interrogate processes that determine these distinct phenotypes and their inheritance pattern, we generated somatic cell fusions and performed integrated genetic and epigenetic (DNA methylation and chromatin) profiling. We found that the basal-like trait is generally dominant and it is largely defined by epigenetic repression of luminal transcription factors. more...
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array
Platform:
GPL6801
19 Samples
Download data: CEL, XLSX
Series
Accession:
GSE39412
ID:
200039412
2.

Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Methylation profiling by array; Genome variation profiling by SNP array; Methylation profiling by genome tiling array
7 related Platforms
106 Samples
Download data: BED, BW, CEL, FPKM_TRACKING, PROBSCOREISLAND, TXT
Series
Accession:
GSE38548
ID:
200038548
3.

[GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 (ucsc=hg18; ncbi=NCBI36) August 01, 2012: annotation table updated with netaffx build 32 (ucsc=hg19; ncbi=GRCh37) Protocol: see manufacturer's web site The new Affymetrix® Genome-Wide Human SNP Array 6.0 features 1.8 million genetic markers, including more than 906,600 single nucleotide polymorphisms (SNPs) and more than 946,000 probes for the detection of copy number variation. more...
Organism:
Homo sapiens
404 Series
22859 Samples
Download data
Platform
Accession:
GPL6801
ID:
100006801
4.

SUM159-MCF7_SNP6

Organism:
Homo sapiens
Source name:
breast cancer cell line heterofusion SUM159PT_MCF7
Platform:
GPL6801
Series:
GSE38548 GSE39412
Download data: CEL
Sample
Accession:
GSM967824
ID:
300967824
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