U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Search results

Items: 1 to 20 of 318

1.

MicroRNA array studies in Hirschsprung disease

(Submitter supplied) To address the role of miRNAs in Hirschsprund disease (HSCR), we carried out microRNA (miRNA) array analysis by using human intestinal samples obtained from HSCR patients and controls, and identified dysregulated miRNAs involved in the pathogenesis of HSCR.
Organism:
Herpesvirus saimiri (strain 11); JC polyomavirus; Human gammaherpesvirus 8; Merkel cell polyomavirus; Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Human betaherpesvirus 6B
Type:
Non-coding RNA profiling by array
Platform:
GPL32145
10 Samples
Download data: GPR, TXT
Series
Accession:
GSE200369
ID:
200200369
2.

Aging aggravates aortic aneurysm and dissection via the miR-1204-MYLK signaling axis

(Submitter supplied) The mechanism by which aging induces aortic aneurysm and dissection (AAD) remains unclear. A total of 430 subjects were recruited for screening of differentially expressed plasma microRNAs. We found that miR-1204 was significantly increased in both plasma and aorta of elder patients with AAD, and was positively correlated with age. Cell senescence induced the expression of miR-1204 through p53 interaction with plasmacytoma variant translocation 1, and miR-1204 induced vascular smooth muscle cell (VSMC) senescence to form a positive feedback loop. more...
Organism:
Human alphaherpesvirus 2; human gammaherpesvirus 4; Human betaherpesvirus 6B; Betapolyomavirus macacae; Herpesvirus saimiri (strain 11); JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus hominis; Homo sapiens; Human alphaherpesvirus 1; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL21439
12 Samples
Download data: GPR, XLSX
Series
Accession:
GSE253747
ID:
200253747
3.

Increased pro-inflammatory phenotype of peripheral blood monocytes and monocyte-derived macrophages among patients with excessive ethanol intake

(Submitter supplied) Excessive alcohol consumption adversely affects the immune system and triggers the activation of peripheral blood (PB) monocytes and tissue macrophages, contributing to alcohol- related organ damage. This study aimed to analyze the M1/M2 and inflammatory phenotypes of circulating monocytes and macrophage-derived monocytes (MDMs). This single-center cross- sectional study included 20 excessive alcohol drinkers (EADs) and 22 healthy controls. more...
Organism:
Rattus norvegicus; Human alphaherpesvirus 2; Merkel cell polyomavirus; Mus musculus cytomegalovirus 2; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL11434
22 Samples
Download data: GPR, TXT
Series
Accession:
GSE239659
ID:
200239659
4.

MiRNAs array after SH3BP2 silencing in Gastrointestinal stromal tumor cells

(Submitter supplied) Silencing of the adaptor SH3BP2 impairs Gastrointestinal stromal tumors growth through miRNAs We dissected SH3BP2 pathway in Gastrointestinal Stromal Tumor cells (GIST) performing a miRNA array in SH3BP2-silenced GIST cells
Organism:
Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Human betaherpesvirus 6B; Betapolyomavirus macacae; Human alphaherpesvirus 2; Betapolyomavirus hominis
Type:
Non-coding RNA profiling by array
Platform:
GPL21599
12 Samples
Download data: TXT, XLSX
Series
Accession:
GSE213777
ID:
200213777
5.

Esrrb Regulates Specific Feed-Forward Loops to Transit from Pluripotency into Early Stages of Differentiation

(Submitter supplied) Characterization of pluripotent states, in which cells can both self-renew or differentiate, with the irreversible loss of pluripotency, are important research areas in developmental biology. Although microRNAs (miRNAs) have been shown to be crucial for embryonic stem (ES) self-renewal maintenance and cellular differentiation, the role of miRNAs integrated into gene regulatory networks and its dynamic changes during these state transitions remain elusive. more...
Organism:
Homo sapiens; Human alphaherpesvirus 1; Human betaherpesvirus 5; Betapolyomavirus hominis; Human alphaherpesvirus 2; Murid gammaherpesvirus 4; Mus musculus; Rattus norvegicus; Murid betaherpesvirus 1; JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; human gammaherpesvirus 4; Human gammaherpesvirus 8; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL18658
12 Samples
Download data: TXT
Series
Accession:
GSE57371
ID:
200057371
6.

MicroRNAs profile in Human Circulating CD4+ T Cells in Patients with Atherosclerosis Obliterans:Healthy persons vs. patients

(Submitter supplied) MicroRNAs profile of circulating CD4+ T Cells in Aged Patients with Atherosclerosis Obliterans comparing healthy persons without symptoms or lesion associated with atherosclerosis.
Organism:
Homo sapiens; Rhadinovirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Human alphaherpesvirus 2; Lymphocryptovirus; JC polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL26002
14 Samples
Download data: GPR, XLSX
Series
Accession:
GSE196698
ID:
200196698
7.

Expression analysis of microRNAs in INT-HA-induced M2-like macrophages and untreated macrophages (M0)

(Submitter supplied) Using the highly sensitive miRNA microarray, we screened 107 up-regulated microRNAs and 33 down-regulated microRNAs in the INT-HA-induced M2-like macrophages and we explored the functions of these miRNAs in macrophage polarization. The enrichment results indicated that these miRNAs might participate in the process of macrophage polarization. Furthermore, the quantitative real-time polymerase chain reaction results showed that miR-935 may play an important role in M2 macrophage polarization which was activated by INT-HA.
Organism:
Human alphaherpesvirus 2; Merkel cell polyomavirus; Herpesvirus saimiri (strain 11); JC polyomavirus; Betapolyomavirus macacae; Homo sapiens; Betapolyomavirus hominis; Human immunodeficiency virus 1; Human betaherpesvirus 6B
Type:
Non-coding RNA profiling by array
Platform:
GPL24594
6 Samples
Download data: GPR
Series
Accession:
GSE110339
ID:
200110339
8.

Differentially expressed microRNAs in the mouse liver with T3 treatment

(Submitter supplied) An improved mechanistic understanding of the thyroid hormone (TH) action on bile acid (BA) synthetic pathway, the major route for cholesterol elimination, will facilitate the identification of novel therapeutic targets for hypercholesterolemia. Here, we show that hepatic miR-378 is positively regulated by TH. Transient overexpression of miR-378 in the liver of mice reduces the serum cholesterol levels, which is accompanied with an upregulation of key enzymes involved in the intrahepatic conversion of cholesterol to BAs. more...
Organism:
Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Rattus norvegicus; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL20794
1 Sample
Download data: TXT, XLS
Series
Accession:
GSE139961
ID:
200139961
9.

The difference of microRNA profiles among control, normal high density lipoprotein-treated and proflammatory high density lipoprotein-treated endothelial cells

(Submitter supplied) The potential mechanism were successfully illustrated through detecting different expression of microRNAs in between proinflammatory high density lipprotein (pHDL), nomal high density lipprotein (nHDL) and control group, to study whether microRNAs play important roles in the endothelial dysfunction caused by pHDL.
Organism:
JC polyomavirus; Homo sapiens; Rhadinovirus; Human alphaherpesvirus 2; Lymphocryptovirus; Merkel cell polyomavirus; Human immunodeficiency virus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL29064
3 Samples
Download data: XLS
Series
Accession:
GSE156800
ID:
200156800
10.

miRNA profile in the hippocampus of APP/PS1 transgenic mice

(Submitter supplied) To explore the miRNAs associated with the memory deficits in Alzheimer's disease, we detected the miRNA profiles in the hippocampus of 6-month-old male APPswe/PS1dE9 (APP/PS1) mice and age-matched wild type C57BL/6 mice.
Organism:
human gammaherpesvirus 4; Herpesvirus saimiri (strain 11); JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae; Betapolyomavirus hominis; Human alphaherpesvirus 2; Human betaherpesvirus 6B; Merkel cell polyomavirus; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Macacine alphaherpesvirus 1; Human betaherpesvirus 5; Human immunodeficiency virus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL21439
6 Samples
Download data: GPR
Series
Accession:
GSE138382
ID:
200138382
11.

Comparison of microRNA expression profiles in soft palate muscle of patients with OSAHS and chronic tonsillitis.

(Submitter supplied) The expression profile of miRNAs in soft palate muscle of patients with OSAHS (obstructive sleep apnea/hypopnea syndrome) and chronic tonsillitis was examined using miRNA microarray analysis. Combining with the following real time PCR and bioinformatics analysis, the physiological importance of the miRNA-autophagy interconnection is far more likely to be elucidated.
Organism:
Human alphaherpesvirus 1; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae; Human alphaherpesvirus 2; JC polyomavirus; Betapolyomavirus hominis; Homo sapiens; Rhadinovirus; Human immunodeficiency virus 1; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL19128
8 Samples
Download data: GPR, TXT
Series
Accession:
GSE99239
ID:
200099239
12.

MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Human alphaherpesvirus 1; Cytomegalovirus; Lymphocryptovirus; Betapolyomavirus macacae; Homo sapiens; Rhadinovirus; Merkel cell polyomavirus; Human immunodeficiency virus 1; Human alphaherpesvirus 2; JC polyomavirus; Betapolyomavirus hominis
Type:
Expression profiling by array; Expression profiling by high throughput sequencing; Non-coding RNA profiling by array; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL18573 GPL571 GPL19128
75 Samples
Download data: CEL, TXT
Series
Accession:
GSE117748
ID:
200117748
13.

MicroRNA-mediated suppression of the TGF-ß pathway confers transmissible and reversible CDK4/6 inhibitor resistance (miRNA array)

(Submitter supplied) CDK4/6 inhibition is now part of the standard armamentarium for patients with estrogen receptor (ER)-positive breast cancer, so that defining mechanisms of resistance is a pressing issue. Here, we identify increased CDK6 expression as a key determinant of acquired resistance after exposure to palbociclib in ER-positive breast cancer cells. Increased CDK6 in resistant cells was dependent on TGF-β pathway suppression via miR-432-5p expression. more...
Organism:
JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Cytomegalovirus; Betapolyomavirus macacae; Homo sapiens; Human alphaherpesvirus 1; Rhadinovirus; Betapolyomavirus hominis; Human alphaherpesvirus 2; Lymphocryptovirus
Type:
Non-coding RNA profiling by array
Platform:
GPL19128
9 Samples
Download data: TXT
Series
Accession:
GSE117745
ID:
200117745
14.

microRNA responses of LPS and IL-10 stimulated primary human monocyte-derived macrophages over a short time-course

(Submitter supplied) Lipopolysaccharide stimulated primary human monocyte-derived macrophages at 2, 4 and 8hrs, IL-10 at 4hrs, IL-10+LPS at 4hrs
Organism:
Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; Rattus norvegicus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL7722
6 Samples
Download data: TXT
Series
Accession:
GSE125572
ID:
200125572
15.

Microarray-based miRNA expression,identified miRNAs that were regulated by KSHV vIRF1

(Submitter supplied) HUVECs were transduced with lentiviral vIRF1 or control lentivirus (pHAGE),microarray-based miRNA expression profiling was adopted and identified a set of miRNAs that were differentially expressed between vIRF1- and pHAGE-transduced HUVECs
Organism:
Homo sapiens; Macacine alphaherpesvirus 1; Merkel cell polyomavirus; Human alphaherpesvirus 1; Human betaherpesvirus 5; human gammaherpesvirus 4; Human betaherpesvirus 6B; Betapolyomavirus macacae; Herpesvirus saimiri (strain 11); JC polyomavirus; Human immunodeficiency virus 1; Human gammaherpesvirus 8; Human alphaherpesvirus 2; Betapolyomavirus hominis
Type:
Non-coding RNA profiling by array
Platforms:
GPL20712 GPL21439
6 Samples
Download data: TXT
Series
Accession:
GSE119034
ID:
200119034
16.

human serum: Control vs. patients with repeated implantation failure

(Submitter supplied) microRNAs profiling of human serum comparing control fertile women with women who had experienced repeated implantation failure after ovarian stimulation and IVF-ET. Repeated implantation failure was defined as women who had undergone≥3 failed cycles with high-grade embryos were transferred.
Organism:
Human alphaherpesvirus 1; Cytomegalovirus; Betapolyomavirus macacae; Human alphaherpesvirus 2; Lymphocryptovirus; Betapolyomavirus hominis; JC polyomavirus; Human immunodeficiency virus 1; Homo sapiens; Rhadinovirus; Merkel cell polyomavirus
Type:
Non-coding RNA profiling by array
Platform:
GPL19128
6 Samples
Download data: GPR, TXT
Series
Accession:
GSE106307
ID:
200106307
17.

Differentially expressed miRNA in biological premature ovarian insufficiency (bPOI)

(Submitter supplied) We first examined changes of miRNAs and expression using microarrays ( Exiqon miRCURY™ microarray LNA v.18.0) of GCs from 10 bPOI and 10 age and BMI matched normal control women. Seventy-five miRNAs (Fold Change [FC]>2, P<0.05) were identified differentially expressed between bPOI patients and control women.
Organism:
JC polyomavirus; Human immunodeficiency virus 1; Merkel cell polyomavirus; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Lymphocryptovirus; Homo sapiens; Rhadinovirus; Betapolyomavirus hominis; Cytomegalovirus; Betapolyomavirus macacae
Type:
Non-coding RNA profiling by array
Platform:
GPL19128
20 Samples
Download data: GPR, TXT
Series
Accession:
GSE100238
ID:
200100238
18.

Mechanical stretch induced transcriptomic profiles in cardiac myocytes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Murid gammaherpesvirus 4; Betapolyomavirus hominis; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae; Rattus norvegicus; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL7722
20 Samples
Download data
Series
Accession:
GSE107380
ID:
200107380
19.

Mechanical stretch induced transcriptomic profiles in cardiac myocytes [24-48 hours]

(Submitter supplied) The effect of cyclic mecanical stretch on cardiac microRNA expression was studied in neonatal rat ventricular myocytes (NRVMs).
Organism:
human gammaherpesvirus 4; Betapolyomavirus macacae; Rattus norvegicus; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus hominis; Murid gammaherpesvirus 4; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL7722
9 Samples
Download data: XLS
Series
Accession:
GSE107379
ID:
200107379
20.

Mechanical stretch induced transcriptomic profiles in cardiac myocytes [1-12 hours]

(Submitter supplied) The effect of cyclic mecanical stretch on cardiac microRNA expression was studied in neonatal rat ventricular myocytes (NRVMs).
Organism:
Mus musculus; Human gammaherpesvirus 8; Rattus norvegicus; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Human alphaherpesvirus 1; human gammaherpesvirus 4; Betapolyomavirus macacae; Homo sapiens; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1
Type:
Non-coding RNA profiling by array
Platform:
GPL7722
11 Samples
Download data: XLS
Series
Accession:
GSE107378
ID:
200107378
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=txid10632[Organism:exp]|query=1|qty=45|blobid=MCID_667051ffce9c6e4cac2793d7|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center