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Items: 1 to 20 of 76

1.

Comparative analysis of small RNAs released by the filarial nematode Litomosoides sigmodontis in vitro and in vivo

(Submitter supplied) BACKGROUND: The release of small non-coding RNAs (sRNAs) has been reported in parasitic nematodes, trematodes and cestodes of medical and veterinary importance. However, little is known regarding the diversity and composition of sRNAs released by different lifecycle stages and the portion of sRNAs that persist in host tissues during filarial infection. This information is relevant to understanding potential roles of sRNAs in parasite-to-host communication, as well as to inform on the location within the host and time point at which they can be detected. more...
Organism:
Meriones unguiculatus; Litomosoides sigmodontis
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL27761 GPL27762
78 Samples
Download data: CSV
Series
Accession:
GSE140538
ID:
200140538
2.

Exosomes secreted by a nematode parasite transfer small RNAs to mammalian cells and regulate genes of the innate immune system [Litomosoides sigmodontis]

(Submitter supplied) In mammalian systems, extracellular small RNAs can operate in a paracrine manner to communicate information between cells, relying on transport within vesicles. “Foreign” small RNAs derived from bacteria, plants and parasites have also been detected in mammalian body fluids, sparking interest in whether these could mediate inter-species communication. However, there is no mechanistic framework for RNA-mediated interspecies communication and the active movement of RNA via vesicles has not been shown outside of mammals. more...
Organism:
Litomosoides sigmodontis
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL19032
2 Samples
Download data: TXT
Series
Accession:
GSE60021
ID:
200060021
3.

Exosomes secreted by a nematode parasite transfer small RNAs to mammalian cells and regulate genes of the innate immune system

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Litomosoides sigmodontis; Heligmosomoides polygyrus
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL18432 GPL19032 GPL18433
12 Samples
Download data: TXT
Series
Accession:
GSE60022
ID:
200060022
4.

Tetracycline-treated Litomosoides sigmodontis vs. untreated control Litomosoides sigmodontis

(Submitter supplied) The filarial nematodes Brugia malayi, Wuchereria bancrofti and Onchocerca volvulus cause elephantiasis, dermatitis and blindness, resulting in severe morbidity in developing countries. 1.3 billion people are at risk of infection. Targeting the essential Wolbachia endobacteria of filarial nematodes with doxycycline has proven to be an effective therapy, resulting in a block in embryogenesis and worm development, and macrofilaricidal effects. more...
Organism:
Wuchereria bancrofti; Wolbachia endosymbiont strain TRS of Brugia malayi; Brugia malayi; Onchocerca volvulus; Litomosoides sigmodontis
Type:
Expression profiling by array
Platform:
GPL10232
6 Samples
Download data: CSV, TXT
Series
Accession:
GSE20976
ID:
200020976
5.

Illumina Genome Analyzer (Litomosoides sigmodontis)

Organism:
Litomosoides sigmodontis
1 Series
62 Samples
Download data
Platform
Accession:
GPL27761
ID:
100027761
6.

Illumina Genome Analyzer IIx (Litomosoides sigmodontis)

Organism:
Litomosoides sigmodontis
2 Series
2 Samples
Download data
Platform
Accession:
GPL19032
ID:
100019032
7.

48-72h_5

Organism:
Litomosoides sigmodontis
Source name:
adult female worms ES products 72h
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173880
ID:
304173880
8.

48-72h_4

Organism:
Litomosoides sigmodontis
Source name:
adult female worms ES products 72h
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173879
ID:
304173879
9.

48-72h_3

Organism:
Litomosoides sigmodontis
Source name:
adult female worms ES products 72h
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173878
ID:
304173878
10.

48-72h_2

Organism:
Litomosoides sigmodontis
Source name:
adult female worms ES products 72h
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173877
ID:
304173877
11.

48-72h_1

Organism:
Litomosoides sigmodontis
Source name:
adult female worms ES products 72h
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173876
ID:
304173876
12.

0-24h_5

Organism:
Litomosoides sigmodontis
Source name:
adult female worms ES products 24h
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173875
ID:
304173875
13.

0-24h_4

Organism:
Litomosoides sigmodontis
Source name:
adult female worms ES products 24h
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173874
ID:
304173874
14.

0-24h_3

Organism:
Litomosoides sigmodontis
Source name:
adult female worms ES products 24h
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173873
ID:
304173873
15.

0-24h_2

Organism:
Litomosoides sigmodontis
Source name:
adult female worms ES products 24h
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173872
ID:
304173872
16.

0-24h_1

Organism:
Litomosoides sigmodontis
Source name:
adult female worms ES products 24h
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173871
ID:
304173871
17.

mf_8_ES

Organism:
Litomosoides sigmodontis
Source name:
microfilariae ES products
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173870
ID:
304173870
18.

mf_7_ES

Organism:
Litomosoides sigmodontis
Source name:
microfilariae ES products
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173869
ID:
304173869
19.

mf_6_ES

Organism:
Litomosoides sigmodontis
Source name:
microfilariae ES products
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173868
ID:
304173868
20.

mf_5_ES

Organism:
Litomosoides sigmodontis
Source name:
microfilariae ES products
Platform:
GPL27761
Series:
GSE140538
Download data: CSV
Sample
Accession:
GSM4173867
ID:
304173867
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