Similar studies for GEO DataSets (Select 200004738) - GEO DataSets

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Items: 20

Select item 2000047381.

Global analysis of gene expression in Xenopus hindlimbs during stage-dependent complete and incomplete regeneration

(Submitter supplied) Xenopus laevis tadpoles are capable of limb regeneration following amputation, in a process which initially involves the formation of a blastema. However, Xenopus has full regenerative capacity only through premetamorphic stages. We have used the Affymetrix Xenopus laevis Genome Genechip® microarray to perform a large-scale screen of gene expression in the regeneration-complete, stage 53 (st53), and regeneration-incomplete, stage 57 (st57), hindlimbs at 1 and 5 days post-amputation. more...

Organism:: Xenopus laevis

Type:: Expression profiling by array

Platform:: GPL1318
16 Samples

Download data

Series

Accession:: GSE4738

ID:: 200004738

Select item 2000098132.

Comparison of regenerating and non regenerating transgenic stage 52 Xenopus hind limbs

(Submitter supplied) Epimorphic regeneration is the process by which complete regeneration of a complex structure such as a limb occurs through production of a proliferating blastema. This type of regeneration is rare among vertebrates but does occur in the African clawed frog Xenopus laevis, traditionally a model organism for the study of early development. Xenopus tadpoles can regenerate tails, limb buds and the lens of the eye, although the ability of the latter two organs to regenerate diminishes with advancing developmental stage. more...

Organism:: Xenopus laevis

Type:: Expression profiling by array

Platform:: GPL1318
4 Samples

Download data: CEL, CHP

Series

Accession:: GSE9813

ID:: 200009813

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000070513.

Expression data for hindlimb and tail samples in a metamorphosis assay for thyroid axis disruption - inhibitors

(Submitter supplied) Thyroid hormones (TH), thyroxine (T4) and 3, 5, 3’-triiodothyronine (T3), play crucial roles in regulation of growth, development and metabolism in vertebrates and are targets for endocrine disruptive agents. Perturbations in TH action can contribute to the development of disease states and the U.S. Environmental Protection Agency is developing a high throughput screen using TH-dependent metamorphosis of the Xenopus laevis tadpole as an assay platform. more...

Organism:: Xenopus laevis; Aquarana catesbeiana

Type:: Expression profiling by array

Platform:: GPL4801
64 Samples

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Series

Accession:: GSE7051

ID:: 200007051

Select item 2000073144.

Expression data from non-infected and Salmonella Choleraesuis infected mesenteric lymph nodes

(Submitter supplied) To understand the host transcriptional response to S. enterica serovar Choleraesuis (S. Choleraesuis), the first generation Affymetrix porcine GeneChip® was used to identify differentially expressed genes in the mesenteric lymph nodes responding to infection at acute (8 hours (h), 24h, 48h post-inoculation (pi)) and chronic stages (21 days (d) pi) The objectives of this study were to identify and examine the stereotypical gene expression response within the host mesenteric lymph nodes to S. more...

Organism:: Sus scrofa

Type:: Expression profiling by array

Platform:: GPL3533
15 Samples

Download data: CEL, EXP

Series

Accession:: GSE7314

ID:: 200007314

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000071295.

Xenopus cDNA microarray identification of genes with endodermal organ expression

(Submitter supplied) The endoderm is classically defined as the innermost layer of three Metazoan germ layers. During organogenesis, the endoderm gives rise to the digestive and respiratory tracts as well as associated organs such as the liver, pancreas, and lung. At present, however, how the endoderm forms the variety of cell types of digestive and respiratory tracts as well as the budding organs is not well understood. more...

Organism:: Xenopus laevis

Type:: Expression profiling by array

Platform:: GPL1861
3 Samples

Download data: TXT

Series

Accession:: GSE7129

ID:: 200007129

Select item 2000108516.

Gene differential expression between attachment and detachment of zebra mussel

(Submitter supplied) A zebra mussel byssus cDNA microarray was used to identify the differentially expressed genes between attachment and detachment. Keywords: Gene differential expression

Organism:: Dreissena polymorpha

Type:: Expression profiling by array

Platform:: GPL6586
4 Samples

Download data: GPR

Series

Accession:: GSE10851

ID:: 200010851

Select item 1000065867.

Zebra mussel byssus cDNA microarray

(Submitter supplied) 716 E.coli clones were selected from thirty-four 96-well plates and re-arranged into eight new 96-well plates. The overnight cultures from the eight 96-well plates were used to prepare the PCR templates. 10 μl of each bacterial culture was taken to mix with 90 μl sterile double distilled water. Then the mixture was incubated at 100 ℃ for 10 minutes followed by 15 minutes 1200g centrifuge. The supernatant was used as PCR templates. more...

Organism:: Dreissena polymorpha

3 Series
62 Samples

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Platform

Accession:: GPL6586

ID:: 100006586

PubMed Similar studies

Select item 2000050508.

Regulation of 22q11 orthologous genes during mouse development

(Submitter supplied) 22q11-deletion syndrome (22q11DS) is a developmental anomaly caused by a microdeletion on human chromosome 22q11. Although mouse models indicated Tbx1 as the gene responsible of the syndrome, the phenotypic spectrum of del22q11 patients is complex suggesting that gene-gene and gene-environment interactions, probably during embryonic development, are crucial in delineating the pathogenesis of 22q11DS. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL3634
14 Samples

Download data

Series

Accession:: GSE5050

ID:: 200005050

Select item 2000121289.

Expression data from ectodermal explants following activation of hormone-inducible zic1

(Submitter supplied) The response of ectodermal explants, neuralized by noggin and treated with cycloheximide, following activation of hormone-inducible zic1 injected into the parent embryos compared to those from beta globin injected embryos as controls, is expected to provide information on the direct targets of the Zic1 transcription factor.

Organism:: Xenopus laevis

Type:: Expression profiling by array

Platform:: GPL1318
5 Samples

Download data: CEL, CHP

Series

Accession:: GSE12128

ID:: 200012128

Select item 20000860210.

Early responsive genes in human amnion epithelial FL cells induced by N-methyl-N’-nitro-N-nitrosoguanidine

(Submitter supplied) The alkylating agent N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) induces cellular DNA damages and other comprehensive alterations that lead to chromosomal aberrations, mutations, tumor initiations, and cell death. However, the molecular mechanism of MNNG-induced cellular stress remains unclear.We have genome-wide analyzed early transcriptional responses of human FL amnion epithelial cells after exposure to three relatively low doses of MNNG (0.2, 1.0, and 10.0µM),and differential gene expression profiles were obtained 4 h after exposure using oligonucleotide microarrays followed by validation with quantitative real-time RT-PCR. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL96 GPL97
16 Samples

Download data: CEL, EXP

Series

Accession:: GSE8602

ID:: 200008602

Select item 20000614011.

Cross platform microarray analysis for robust identification of differentially expressed genes

(Submitter supplied) Microarrays have been widely used for the analysis of gene expression and several commercial platforms are available. The combined use of multiple platforms can overcome the inherent biases of each approach, and may represent an alternative that is complementary to RT-PCR for identification of the more robust changes in gene expression profiles. In this paper, we combined statistical and functional analysis for the cross platform validation of two oligonucleotide-based technologies, Affymetrix (AFFX) and Applied Biosystems (ABI), and for the identification of differentially expressed genes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL570 GPL1426
12 Samples

Download data: CEL

Series

Accession:: GSE6140

ID:: 200006140

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20001442412.

Age-Dependent Differences in Gene Expression in Response to Calvarial Injury

(Submitter supplied) Children less than 2 years of age are capable of healing large calvarial defects, whereas adults have been found to lack this endogenous ability. In this study, we used microarray analysis to compare genomewide expression patterns during active regeneration after injury with calvaria in skeletally immature and mature mice. Parietal bone defects were created in 6-day-old (juvenile) and 60-day-old (adult) mice using a 4-mm trephine bit (n = 20 mice per age group). more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL8077
2 Samples

Download data

Series

Accession:: GSE14424

ID:: 200014424

Select item 20001799313.

Zebrafish heart regeneration

(Submitter supplied) Ischemic cardiopathy is the leading cause of death in the world, for which efficient regenerative therapy is not currently available. In mammals, after a myocardial infarction episode, the damaged myocardium is replaced by scar tissue featuring collagen deposition and tissue remodelling with negligible cardiomyocyte proliferation. Zebrafish, in contrast, display an extensive regenerative capacity as they are able to restore completely lost cardiac tissue after partial ventricular amputation. more...

Organism:: Danio rerio

Type:: Expression profiling by array

Dataset:: GDS3623
Platform:: GPL1319
15 Samples

Download data: CEL

Series

Accession:: GSE17993

ID:: 200017993

Select item 362314.

Heart regeneration in zebrafish

Analysis of hearts of zebrafish 1 to 7 days following partial heart amputation. Unlike mammals, zebrafish hearts display an extensive regenerative capacity. Results provide insight into the molecular basis of this regenerative capacity.

Organism:: Danio rerio

Type:: Expression profiling by array, transformed count, 2 protocol, 5 time sets

Platform:: GPL1319
Series:: GSE17993
15 Samples

Download data: CEL

DataSet

Accession:: GDS3623

ID:: 3623

Select item 20003776715.

Expression data from juvenile Xenopus laevis inner ear tissue

(Submitter supplied) We implemented a functional genomics approach as a means to undertake a large-scale analysis of the Xenopus laevis inner ear transcriptome through microarray analysis. Microarray analysis uncovered genes within the X. laevis inner ear transcriptome associated with inner ear function and impairment in other organisms, thereby supporting the inclusion of Xenopus in cross-species genetic studies of the inner ear.

Organism:: Xenopus laevis

Type:: Expression profiling by array

Platform:: GPL1318
3 Samples

Download data: CEL

Series

Accession:: GSE37767

ID:: 200037767

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007382916.

Inner ear expression data from pooled inner ear tissue from stages 56,57,58 Xenopus laevis larval inner ears

(Submitter supplied) The inner ear continues to grow and develop until the auditory and vestibular systems reach full maturity and all of the genes involved in this process have yet to be identified. Previous gene based analysis have primarily focused on the early developmental stages following induction and initial formation of the inner ear. The aim of this study is to identify new candidate genes for inner ear development. more...

Organism:: Xenopus laevis

Type:: Expression profiling by array

Platform:: GPL10756
3 Samples

Download data: CEL

Series

Accession:: GSE73829

ID:: 200073829

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20006970117.

RNA-Seq and microarray analysis of the Xenopus inner ear transcriptome discloses orthologous OMIM® genes for hereditary disorders of hearing and balance

(Submitter supplied) Purpose: To identify orthologous genes in Xenopus that are implicated in deafness and vestibular disorders in humans and to compare RNA-Seq and microarray to determine the advantages of each technology for Xenopus transcriptomic analysis. Methods: Inner ear RNA from X. laevis stages 56-58 was isolated with the Qiagen® RNeasy® Mini Kit. RNA quality was assessed using the Agilent 2100 Bioanalyzer. The RNA was sent to the National Center for Genome Resources, for Illumina-Solexa sequencing using the genome analyzer II and to MIT for microarray processing usign the Affymetrix GeneChip® X. more...

Organism:: Xenopus laevis

Type:: Expression profiling by high throughput sequencing

Platform:: GPL14834
1 Sample

Download data: TXT

Series

Accession:: GSE69701

ID:: 200069701

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20011845418.

Brief Local Application of Progesterone via a Wearable Bioreactor Induces Long-Term Regenerative Response in Adult Xenopus Hindlimb

(Submitter supplied) The induction of limb repair depends on signals that initiate regeneration and the successful transmission of those signals in vivo. Here, we characterize the effects of an integrated device-based in vivo delivery of drug compounds in adult Xenopus laevis, which normally regenerate only a cartilaginous spike after limb amputation. A wearable bioreactor containing a silk protein-based hydrogel containing progesterone that was applied to the wound site immediately after hind-limb amputation for 24 hours induced regeneration of flattened paddle-like structures in adult frogs. more...

Organism:: Xenopus laevis

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17682
27 Samples

Download data: XLSX

Series

Accession:: GSE118454

ID:: 200118454

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20001262519.

Expression data for a study on cross-species hybridization on single-species microarrays

(Submitter supplied) Gene expression was examined in testis and brain tissue between two species (Xenopus laevis and Xenopus borealis) and their hybrid. Genomic DNA hybridizations of the microarray target and non-target species were used to select probes that are unbiased between species.

Organism:: Xenopus laevis; Xenopus muelleri; Xenopus laevis x Xenopus borealis; Xenopus borealis

Type:: Expression profiling by array; Genome variation profiling by array

Platform:: GPL1318
15 Samples

Download data: CEL, TXT

Series

Accession:: GSE12625

ID:: 200012625

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20008897520.

RNA-Seq of Xenopus tail regeneration

(Submitter supplied) In contrast to humans, many amphibians are able to rapidly and completely regenerate complex tissues, including complete appendages. Following tail amputation, Xenopus tropicalis tadpoles quickly regenerate muscle, spinal cord, cartilage, vasculature and skin, all properly patterned in three dimensions. To better understand the molecular basis of this regenerative competence, we performed a transcriptional analysis of regeneration using RNA-Seq. more...

Organism:: Xenopus tropicalis

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21874
10 Samples

Download data: TXT

Series

Accession:: GSE88975

ID:: 200088975

PubMed Similar studies SRA Run Selector

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