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Mapping genotypes to chromatin accessibility profiles in single cells
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Single-Cell Genotyping of Transcriptomes
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Amplicon of Single-Cell Genotyping of Transcriptomes
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Effects of the treatment with pegIFNa, Azacytidine or pegIFNa+Azacytidine in LT-HSCs from JAK2-V617F MPN mice or JAK2-V617F;Dnmt3a-KO MPN mice.
Gene expression profile at single cell level of phenotypic LT-HSCs from single-mutant JAK2 V617F and double mutant JAK2 V617F;Dnmt3a-/- mice
Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis
Next Generation Sequencing of long-term hematopoietic cells (LT-HSCs) with or without mutations in JAK2 and Ezh2
Next Generation Sequencing of megakaryocyte-erythrocyte progenitor cells (MEPs) with or without mutations in JAK2 and Ezh2
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and JAK2-V617F expressing hematopoietic stem and progenitor subsets
Metabolic Alterations in JAK2 Mutant Hematopoietic Cells Represent Therapeutic Vulnerabilities for Myeloproliferative Neoplasms
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq]
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk ATAC-Seq]
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [scATAC-Seq]
The Aim2 inflammasome and Gasdermin D promote atherosclerotic plaque necrosis in Jak2V617F clonal hematopoiesis
GTAC enables parallel genotyping of multiple genomic loci with chromatin accessibility profiling in single cells
Dynamics of Chromatin Accessibility during Hematopoietic Stem Cell Differentiation into Lineage-Committed Progeny
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