GEO DataSets

(Submitter supplied) Selective breeding of domestic dogs has generated diverse breeds often optimized for performing specialized tasks. Despite the heritability of breed-typical behavioral traits, identification of causal loci has proven challenging due to the complexity of canine population structure. We overcome longstanding difficulties in identifying genetic drivers of canine behavior by developing an innovative framework for understanding relationships between breeds and the behaviors that define them utilizing genetic data for over 4,000 domestic, semi-feral and wild canids and behavioral survey data for over 46,000 dogs. more...

Organism:

Canis lupus familiaris; Canis lupus; Canis lupus dingo

Type:

SNP genotyping by SNP array; Genome variation profiling by SNP array

Platform:

GPL17481

956 Samples

Download data: IDAT, TXT

(Submitter supplied) SNP of new dog breeds improves the validity of population clustering and breed based phylogenies.

Organism:

Canis lupus familiaris

Type:

SNP genotyping by SNP array; Genome variation profiling by SNP array

Platform:

GPL17481

95 Samples

Download data: IDAT, TXT

(Submitter supplied) Analysis of genotypes at 150,000 SNPs reveals patterns of allele and haplotype sharing that describes the breed relationships and development of 161 breeds of dog.

Organism:

Canis lupus familiaris

Type:

Genome variation profiling by SNP array

Platform:

GPL17481

158 Samples

Download data: IDAT, TXT

(Submitter supplied) Building demographic profiles in domestic dog breeds to optimize genetic trait mapping study design

Organism:

Canis lupus; Canis lupus familiaris

Type:

SNP genotyping by SNP array; Genome variation profiling by SNP array

Platform:

GPL17481

795 Samples

Download data: IDAT, TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Canis lupus familiaris

Type:

Genome variation profiling by SNP array; SNP genotyping by SNP array

Platform:

GPL17481

137 Samples

Download data: IDAT

(Submitter supplied) Whole genome sequencing of CTVT, breed dogs, and wild canids reveals pathways that are important in cancer cell survival. Comparison of these mutations with breed dogs shows that the original tumor came from a dog very similar to one of the modern Arctic breeds.

Organism:

Canis lupus familiaris

Type:

Genome variation profiling by SNP array

Platform:

GPL17481

20 Samples

Download data: IDAT, TXT

(Submitter supplied) Allele frequency analysis reveals that the breed is enhanced for genes controlling traits associated with the poodle-type coat, which are perceived to have an association with hypoallergenicity, with no strong signatures of selection for Labrador retriever (LAB) traits. This study provides a blueprint for understanding how dog breeds are formed, highlighting the limited scope of trait selection in defining seemingly new breeds.

Organism:

Canis lupus familiaris

Type:

Genome variation profiling by SNP array; SNP genotyping by SNP array

Platform:

GPL17481

47 Samples

Download data: IDAT, TXT

(Submitter supplied) DNA structural variation (SV) comprises a major portion of genetic diversity, but its biological impact is unclear. We propose that the genetic history and extraordinary phenotypic variation of dogs make them an ideal mammal in which to study the effects of SV on biology and disease. The hundreds of existing dog breeds were created by selection of extreme morphological and behavioral traits. And along with those traits, each breed carries increased risk for different diseases. more...

Organism:

Canis lupus familiaris

Type:

Genome variation profiling by genome tiling array

Platform:

GPL9314

10 Samples

Download data: PAIR

(Submitter supplied) Through thousands of years of breeding and strong human selection, the dog (Canis lupus familiaris) exists today within hundreds of closed populations throughout the world, each with defined phenotypes. A singular geographic region with broad diversity in dog breeds presents an interesting opportunity to observe potential mechanisms of breed formation. Italy claims 14 internationally recognized dog breeds, with numerous additional local varieties. more...

Organism:

Canis lupus familiaris

Type:

Genome variation profiling by SNP array; SNP genotyping by SNP array

Platform:

GPL17481

273 Samples

Download data: IDAT, TXT

(Submitter supplied) This study used two different NimbleGen platforms to identify canine CNVs. The first identifies genome-wide CNVs while the second genotypes all known canine CNVs in a large panel of dogs from multiple breeds.

Organism:

Canis lupus; Canis lupus familiaris

Type:

Genome variation profiling by genome tiling array

Platforms:

GPL11335 GPL11333

75 Samples

Download data: PAIR

(Submitter supplied) Diverse dataset of 1247 dogs from many breeds and wolves used to investigate the origins of dog domestication

Organism:

Canis lupus familiaris; Canis lupus

Type:

SNP genotyping by SNP array

Platform:

GPL18091

1239 Samples

Download data: CEL, CHP, TXT