Similar studies for GEO DataSets (Select 3481) - GEO DataSets

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Items: 20

Select item 34811.

NOR1 gene and EWS/NOR1 fusion gene overexpression

Analysis of cells overexpressing NOR1 or the EWS/NOR1 fusion gene. NOR1 encodes an orphan nuclear receptor. The EWS gene is involved in various malignancies by way of chromosomal translocations, and the EWS/NOR1 gene fusion is implicated in the pathogenesis of extraskeletal myxoid chondrosarcomas.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 protocol sets

Platform:: GPL570
Series:: GSE11185
4 Samples

Download data: CEL

DataSet

Accession:: GDS3481

ID:: 3481

Select item 2000111852.

Differences between NOR1 and EWS/NOR1

(Submitter supplied) To examine the differences between NOR1 and its fusion gene product EWS/NOR1, we compared the gene expression profiles of NOR1- and EWS/NOR1-overexpressing 293 cells. Keywords: gene comparison

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3481
Platform:: GPL570
4 Samples

Download data: CEL

Series

Accession:: GSE11185

ID:: 200011185

Select item 2000704173.

Genome-wide ChIP-seq analysis of Nr4a1 binding sites in regulatory T (Treg) cells

(Submitter supplied) We have revealed that Nr4a family nuclear orphan receptors broadly regulate a transcriptional program in Treg cells. In this study, to give an insight into Nr4a-mediated regulation of the transcriptional program in Treg cells, we performed ChIP-seq experiment using anti-Nr4a1 antibodies and a chromatin lysate from Treg cells.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11002
1 Sample

Download data: TXT

Series

Accession:: GSE70417

ID:: 200070417

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000703064.

Comparison of mRNA expression pattern between wild-type regulatory T (Treg) cells and Nr4a-deficient Treg cells

(Submitter supplied) Regulatory T (Treg) cells, as central mediators of immune suppression, play crucial roles in many aspects of immune system physiology and pathophysiology. Treg cells are characterized by a distinct pattern of gene expression, including upregulation of immune-suppressive genes and silencing of inflammatory cytokine genes. However, the molecular mechanisms that establish and/or maintain such gene regulation in Treg cells remain largely unknown. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11202
2 Samples

Download data: TXT

Series

Accession:: GSE70306

ID:: 200070306

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001237395.

Nr4a transcription factors limit CAR-T cell function in solid tumors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL17021
138 Samples

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Series

Accession:: GSE123739

ID:: 200123739

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Select item 2001237386.

Nr4a transcription factors limit CAR-T cell function in solid tumors [RNA-Seq]

(Submitter supplied) Chromatin accessibility with ATAC-seq and gene expression with RNA-seq for CD8 T cells expressing chimeric antigen receptors in solid tumors or after in vitro culture.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17021
47 Samples

Download data: TSV

Series

Accession:: GSE123738

ID:: 200123738

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001236297.

Nr4a transcription factors limit CAR-T cell function in solid tumors [ATAC-Seq]

(Submitter supplied) Chromatin accessibility with ATAC-seq and gene expression with RNA-seq for CD8 T cells expressing chimeric antigen receptors in solid tumors or after in vitro culture.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL17021
91 Samples

Download data: TSV

Series

Accession:: GSE123629

ID:: 200123629

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Select item 2001783918.

Transcriptional profiling of monocytes deficient in Nuclear Orphan Receptors NR4A2 and NR4A3 reveals distinct signalling roles related to antigen presentation and viral response.

(Submitter supplied) Using RNA-sequencing and strategic bioinformatic analysis we investigated the down-stream effects of NR4A2 and NR4A3 in monocytes and dissected their common and distinct signalling roles.NR4A2 selective genes were most associated with antigen presentation, NR4A3 selective genes were most associated with interferon/viral reponse and NR4A2/3 co-regulated genes were most associated with clasical innate immure response signaling e.g. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
18 Samples

Download data: TXT

Series

Accession:: GSE178391

ID:: 200178391

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2000871949.

Schizophrenia: postmortem dorsal lateral prefrontal cortex (DLPFC)

(Submitter supplied) RNA-Seq analysis of post-mortem tissue from DLPFC of 19 schizophrenia patients and 19 controls.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13393
38 Samples

Download data: TXT

Series

Accession:: GSE87194

ID:: 200087194

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20007349210.

EWS and FUS Bind a Subset of Transcribed Genes Encoding Proteins Enriched in RNA Regulatory Functions

(Submitter supplied) Background FUS (TLS) and EWS (EWSR1) belong to the FET-protein family of RNA and DNA binding proteins. FUS and EWS are structurally and functionally related and participate in transcriptional regulation and RNA splicing. FUS and EWS are identified in translocation generated cancer fusion proteins and involved in the human neurological diseases amyotrophic lateral sclerosis and fronto-temporal lobar degeneration. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL9052
5 Samples

Download data: BED, TAR, XLS

Series

Accession:: GSE73492

ID:: 200073492

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Select item 20025192511.

NR4A2 and NR4A3 selectively modulate elements of the monocyte response to buffered hypercapnia

(Submitter supplied) In wild type, NR4A2-deficient, and NR4A3-deficient monocytes we used RNA-sequencing to investigate the effect of 4hrs of exposure to buffered hypercapnia (10% CO2) compared to normocapnia (5% CO2) with and without the pro-inflammatory stimulus LPS (2.5ug/ml) for the final 2hrs. Buffered hypercapnia causes transcriptional changes associated with altered metabolic function in both the basal and stimulated states.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
36 Samples

Download data: TXT

Series

Accession:: GSE251925

ID:: 200251925

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20020633312.

Buffered hypercapnia alters the transcriptional profile in monocytes.

(Submitter supplied) In monocytes we used RNA-sequencing to investigate the effect of 4hrs of exposure to buffered hypercapnia (10% CO2) compared to normocapnia (5% CO2) with and without the pro-inflammatory stimulus LPS (2.5ug/ml) for the final 2hrs. Buffered hypercapnia causes transcriptional changes associated with altered metabolic function in both the basal and stimulated states.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
12 Samples

Download data: TXT

Series

Accession:: GSE206333

ID:: 200206333

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20014674713.

Regulation of Ag-activated B cells by Nur77/Nr4a1

(Submitter supplied) We identify differentially expressed inducible genes in activated B cells harvested from mice lacking expression of the orphan nuclear hormone receptor Nr4a1.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17021
10 Samples

Download data: TXT

Series

Accession:: GSE146747

ID:: 200146747

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Select item 20007374114.

KLF15 dependent REV-ERBa binding in the heart

(Submitter supplied) By comparing the ChIPseq signal of REV_ERBa in control (Flox) and cardiomyocytic KLF15 knockout (cKO), we identified the KLF15 dependent REV-ERBa binding and repression in the heart. We further compared the differential binding sites to KLF15 binding site, using a FLAG tagged cardiomyocytic transgenic (cTG1) mice.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL17021
6 Samples

Download data: BEDGRAPH

Series

Accession:: GSE73741

ID:: 200073741

PubMed Similar studies SRA Run Selector

Select item 20006324315.

KLF15 Establishes the Landscape of Circadian Expression in the Heart

(Submitter supplied) In the heart, KLF15 directs a biphasic circadian rhythm, while preventing extraneous oscillation at the transcriptomic level.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17021
36 Samples

Download data: TXT

Series

Accession:: GSE63243

ID:: 200063243

PubMed Similar studies SRA Run Selector

Select item 20022287716.

Differential binding of PARP-1 domains

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Drosophila melanogaster

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL25244
24 Samples

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Series

Accession:: GSE222877

ID:: 200222877

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Select item 20022287617.

Differential binding of PARP-1 domains (AW-YFP ChIP-seq)

(Submitter supplied) We interrogated the differential binding of PARP-1 domains (ZnI, ZnII, AD-WGR) and a ZnI mutant in Drosophila via ChIP-seq of third-instar larvae.

Organism:: Drosophila melanogaster

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL25244
6 Samples

Download data: BIGWIG

Series

Accession:: GSE222876

ID:: 200222876

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Select item 20022287518.

Differential binding of PARP-1 domains (ZNII-YFP ChIP-seq)

(Submitter supplied) We interrogated the differential binding of PARP-1 domains (ZnI, ZnII, AD-WGR) and a ZnI mutant in Drosophila via ChIP-seq of third-instar larvae.

Organism:: Drosophila melanogaster

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL25244
6 Samples

Download data: BIGWIG

Series

Accession:: GSE222875

ID:: 200222875

PubMed Full text in PMC Similar studies

Select item 20022287319.

Differential binding of PARP-1 domains (ZNI-YFP ChIP-seq)

(Submitter supplied) We interrogated the differential binding of PARP-1 domains (ZnI, ZnII, AD-WGR) and a ZnI mutant in Drosophila via ChIP-seq of third-instar larvae.

Organism:: Drosophila melanogaster

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL25244
6 Samples

Download data: BIGWIG

Series

Accession:: GSE222873

ID:: 200222873

PubMed Full text in PMC Similar studies

Select item 20022286520.

Differential binding of PARP-1 domains (DZNI-YFP ChIP-seq)

(Submitter supplied) We interrogated the differential binding of PARP-1 domains (ZnI, ZnII, AD-WGR) and a ZnI mutant in Drosophila via ChIP-seq of third-instar larvae.