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Or13c7c olfactory receptor family 13 subfamily C member 7C [ Mus musculus (house mouse) ]

Gene ID: 100040268, updated on 17-Aug-2024

Summary

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Official Symbol
Or13c7cprovided by MGI
Official Full Name
olfactory receptor family 13 subfamily C member 7Cprovided by MGI
Primary source
MGI:MGI:1352684
See related
Ensembl:ENSMUSG00000111611 AllianceGenome:MGI:1352684
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Or37c; Olfr157; Olfr37c; Mor262-12
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Or13c7c in Genome Data Viewer
Location:
4 B1; 4 23.05 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (43834752..43837643, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (43834752..43837643, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 13 subfamily C member 7B Neighboring gene predicted gene, 30318 Neighboring gene olfactory receptor family 13 subfamily C member 7 Neighboring gene reversion-inducing-cysteine-rich protein with kazal motifs

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Promotor elements governing the clustered expression pattern of odorant receptor genes. Zhang YQ, et al. Mol Cell Neurosci, 2007 Sep. PMID 17656108
  2. Identification of a natural source for the OR37B ligand. Bautze V, et al. Chem Senses, 2014 Jan. PMID 24235213
  3. Brain targeting and glomerulus formation of two olfactory neuron populations expressing related receptor types. Conzelmann S, et al. Eur J Neurosci, 2001 Nov. PMID 11860457
  4. Local permutations in the glomerular array of the mouse olfactory bulb. Strotmann J, et al. J Neurosci, 2000 Sep 15. PMID 10995837, Free PMC Article
  5. The patch-like pattern of OR37 receptors is formed by turning off gene expression in non-appropriate areas. Strotmann J, et al. Mol Cell Neurosci, 2009 Aug. PMID 19463954

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (4)  1 citation

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
enables olfactory receptor activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within sensory perception of smell ISA
Inferred from Sequence Alignment
more info
 PubMed 
acts_upstream_of_or_within sensory perception of smell TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISA
Inferred from Sequence Alignment
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
olfactory receptor 157
Names
GA_x6K02T2N78B-16110014-16110970
olfactory receptor 37c
olfactory receptor MOR262-12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019475.3 → NP_062348.1  olfactory receptor 157

    See identical proteins and their annotated locations for NP_062348.1

    Status: VALIDATED

    Source sequence(s)
    AL773539
    Consensus CDS
    CCDS18114.1
    UniProtKB/TrEMBL
    Q9QZ20, Q9QZ21
    Related
    ENSMUSP00000150429.2, ENSMUST00000215442.2
    Conserved Domains (1) summary
    cd15430
    Location:25 → 300
    7tmA_OR13-like; olfactory receptor family 13 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    43834752..43837643 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537504.1 → XP_006537567.1  olfactory receptor 157 isoform X1

    See identical proteins and their annotated locations for XP_006537567.1

    UniProtKB/TrEMBL
    Q9QZ20, Q9QZ21
    Related
    ENSMUSP00000149336.2, ENSMUST00000214281.2
    Conserved Domains (1) summary
    cd15430
    Location:25 → 300
    7tmA_OR13-like; olfactory receptor family 13 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version

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