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Pramel61 PRAME like 60 [ Mus musculus (house mouse) ]

Gene ID: 100041077, updated on 2-Nov-2024

Summary

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Official Symbol
Pramel61provided by MGI
Official Full Name
PRAME like 60provided by MGI
Primary source
MGI:MGI:3703005
See related
Ensembl:ENSMUSG00000073723 AllianceGenome:MGI:3703005
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm13102
Summary
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to several human genes including PRAMEF1 (PRAME family member 1); PRAMEF10 (PRAME family member 10); and PRAMEF11 (PRAME family member 11). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
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Genomic context

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See Pramel61 in Genome Data Viewer
Location:
4 E1; 4 77.98 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (143826450..143836671)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (144099880..144110101)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene zinc finger, MYND domain containing 11 pseudogene Neighboring gene PRAME like 4 Neighboring gene STARR-seq mESC enhancer starr_11979 Neighboring gene STARR-seq mESC enhancer starr_11980 Neighboring gene oogenesin 3 Neighboring gene oogenesin 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC164223, MGC164251

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables ubiquitin-like ligase-substrate adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-like ligase-substrate adaptor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Cul2-RING ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Cul2-RING ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC100041077

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085419.1 → NP_001078888.1  uncharacterized protein LOC100041077

    See identical proteins and their annotated locations for NP_001078888.1

    Status: VALIDATED

    Source sequence(s)
    AL928630, AU020510, BC132592
    Consensus CDS
    CCDS57309.1
    UniProtKB/TrEMBL
    A2ASJ3, E0CXV0, F6SEH0, L7MU15, Q3ULC4
    Related
    ENSMUSP00000095408.4, ENSMUST00000097799.10
    Conserved Domains (1) summary
    sd00033
    Location:240 → 275
    LRR_RI; leucine-rich repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    143826450..143836671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319879.1 → XP_017175368.1  uncharacterized protein LOC100041077 isoform X1

    UniProtKB/TrEMBL
    L7MU15
    Conserved Domains (1) summary
    sd00033
    Location:240 → 275
    LRR_RI; leucine-rich repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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